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BLOCK BIOSCIENCES

Intercepting the
spread of cancers to the brain

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Shifting from Reaction to Prevention

At Block Biosciences, we are developing first-in-class therapeutics designed to intercept the spread of cancer to the brain. 

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Addressing a targetable vulnerability

We've identified and are inhibiting a key step in the purine biosynthesis pathway, which is essential for cancer cells to initiate brain metastases.

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Guided by clinically-validated models

Our drug discovery is powered by a unique library of clinically-relevant models, specifically developed to study brain metastasis.

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Building a brighter future

Our technology has the potential to reduce the risk of forming a secondary brain metastasis, one of the deadliest forms of brain cancer.

Our Technology

We leverage clinically-validated models and a deep understanding of metastatic biology to design precision therapeutics.

 

Our technology platforms are designed to accelerate research, enhance diagnostics, and bring novel therapies to fruition. 

Our focus is on creating advancements that have the potential to revolutionize healthcare and enable more patients to not only survive cancer but to reclaim their futures.

Developing BBB-Permeable Inhibitors

Our drugs are uniquely designed to reach the brain, overcoming a major treatment challenge.

Team

Our Team

Amie Phinney, PhD, MBA

Amie Phinney, PhD, MBA

Co-Founder and CEO

Agata Kieliszek, PhD

Agata Kieliszek, PhD

Co-Founder and Head of Biology and Operations

Sheila Singh, MD, PhD, FRSC

Sheila Singh, MD, PhD, FRSC

Co-Founder and CSO

Mathew Piotrowski, PhD

Mathew Piotrowski, PhD

Co-Founder and Senior Scientist

Jakob Magolan, PhD

Jakob Magolan, PhD

Co-Founder and Head of Chemistry

Meet The
Experts

News & Media

Follow our progress. Here you'll find announcements on our research breakthroughs, leadership developments, and key industry recognition as we advance our therapeutic pipeline.

News & Media
Contact Us

Get In Touch

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McMaster Innovation Park

175 Longwood Rd S. Suite 214

Hamilton, ON, L8P0A1

© Block Biosciences Inc . 2025. All rights reserved.

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